Cell Signaling And Immune Cell Involvement In Neointima Formation Connexin (Cx) proteins form gap junctions, allowing for communication between cells. Alterations in gap junctions have been associated with pathological proliferation in disease since their discovery in the 1950s. Our studies … Read More

Lessons from the adverse events reporting in ODYSSEY Outcomes, a large, placebo-controlled, randomized clinical trial of an LDL-lowering agent - Discuss rigor and value of adverse event reporting from randomized clinical trials for exploratory analyses and hypothesis-generating results. - Discuss adverse … Read More

Novel transgenic/chemogenetic models of oxidative stress in the cardiovascular system Dr. Michel’s seminar will discuss the development and application of chemogenetic approaches to dynamically modulate tissue-specific oxidative stress.  These studies have yielded new models of heart failure, neurodegeneration, and aortic … Read More

Extracellular vesicle-mediated communication in cardiovascular disease Extracellular vesicles (EVs) are produced by cells in the cardiovascular system, and they can be taken up by recipient cells to alter function. The contents and functions of EVs change during disease, and they … Read More